AIPAMPDS

Welcome to AIPAMPDS

AIPAMPDS (AI-Powered Antimicrobial Peptide Discovery System) is an integrated tool for generating and screening antimicrobial peptides. This platform combines state-of-the-art machine learning models to help researchers discover and evaluate novel AMPs.

Features

🧬 AMP Generation

Generate novel antimicrobial peptides (AMPs) from scratch using GPT-based models with three generation objectives:

  • Broad-spectrum AMPs: peptides with activity against a wide range of bacterial species.
  • Gram-negative-specific AMPs: peptides optimized for activity against Gram-negative bacteria.
  • Gram-positive-specific AMPs: peptides optimized for activity against Gram-positive bacteria.

Customize peptide length (10-50 amino acids) and quantity (1-1000 sequences).

Generate AMPs

🔬 Comprehensive Screening

Screen your peptide sequences through multiple prediction models:

  • AMP Identifier: Predict antimicrobial activity
  • MIC Predictor: Estimate MIC for E.coli and S.aureus
  • Hemolysis Predictor: Evaluate hemolytic toxicity

Support for FASTA file upload or direct sequence input (max 10000 sequences).

Screen Sequences

⏱️ Job Tracking

Monitor the progress of your analysis jobs in real-time:

  • View status of submitted tasks
  • Track progress percentage
  • Download results when complete
  • Automatic cleanup after 30 days

Results are stored in CSV format with detailed predictions and properties.

Check Job Status

How to Use

For AMP Generation:

  1. Navigate to the Generation page
  2. Select a target (Broad-spectrum, Gram-negative-specific, or Gram-positive-specific)
  3. Specify the desired peptide length (10-50 amino acids)
  4. Choose the number of sequences to generate (1-1000)
  5. Submit the job and note the Job ID
  6. Wait for the job to finish and view the results, or record the Job ID and check the results later on the Job Status page
  7. Download the results CSV file when complete

For Sequence Screening:

  1. Navigate to the Screening page
  2. Either paste sequences directly or upload a FASTA file
  3. Submit the job and note the Job ID
  4. Wait for the job to finish and view the results, or record the Job ID and check the results later on the Job Status page
  5. Download the results CSV file when complete

About the Models

Our platform integrates four specialized deep learning models:

Note: Job results are automatically deleted after 30 days. Please download your results promptly.